Adipoz Doku ve Adissp (Adipose Secreted Signaling Protein)

Reşat Dikme

doi:10.5281/zenodo.10905679

Yazarlar

Reşat Dikme Harran Üniversitesi

DOI:

https://doi.org/10.5281/zenodo.10905679

Anahtar Kelimeler:

Adissp, Adipose Secreted Signaling Protein, Yağ Dokusu, Kardiyovasküler Hastalıklar

Özet

Adissp (Adipose Secreted Signaling Protein) yağ dokusundan salınan bir protein olup, beyaz yağ dokusunun termogenezisini ve glukoz homeostazını düzenleyen önemli bir adipokin olarak bilinmektedir. Adissp, termogenezisi artırarak glukoz homeostazını iyileştirir ve korur. Adissp ayrıca obezite ile ilişkili sistemik metabolik bozukluklara katkıda bulunan yağ dokusundan salınan biyoaktif bir madde olarak görev yapar. Obezite durumunda yağ dokusundan salınan adipokinlerin üretiminde veya salınımında bozukluklar, birçok hastalığın komplikasyonlarına neden olabilmekte, yaşam koşullarının kalitesini düşürebilmekte ve mortalite oranını artırabilmektedir. Bu protein, yağ dokusundan salınan ve metabolik etkilere sahip olan önemli bir moleküldür. Bu derlemede yağ dokusu ve Adissp hakkında bilgiler verilmiştir.

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